Bienvenue sur institut-baulieu.org
J’inaugure ce blog de Président de l’ « Institut Baulieu »,
et vous souhaite la bienvenue sur cet espace. Ce site, et plus
généralement l’Institut, ont été créés avec une ambition principale : aider,
grâce à la recherche biomédicale, à retarder le moment de la
dépendance, cette terrible condition qui peut atteindre la moitié
d’entre nous après 85 ans (et qui en menace beaucoup avant).
Mes recherches passées et actuelles ont permis de faire une observation inédite : contrairement à ce que l’on croyait jusqu’alors, les conséquences du vieillissement du cerveau ne sont pas toutes irréversibles. Nous avons démontré qu’en administrant une hormone fabriquée dans le cerveau et déficitaire avec l’âge, on pouvait, chez le rat et la souris, leur permettre de retrouver une partie de leur faculté de mémoire, diminuée par le seul effet du vieillissement. Nous voulons savoir s’il en est de même chez l’homme, pour faire à partir de ce composé un traitement efficace, une « pilule de mémoire ».
La perte de la mémoire, donc l’abandon de la personnalité et de la dignité de l’individu, est tellement douloureuse pour la personne elle-même et insupportable, psychologiquement et économiquement, à sa famille et à son entourage…. Pour le pays entier, la charge que représente l’accompagnement médico-social, en structures d’accueil, en personnels aidant, est croissante de façon exponentielle.
L’urgence aujourd’hui, comme on ne sait pas encore guérir ni empêcher les altérations de la maladie d’Alzheimer et des autres maladies de dégénérescence cérébrale, c’est de retarder et même d’amoindrir les dégâts qu’elles provoquent. Cette stratégie scientifique peut paraître modeste : elle vise à permettre aux malades de vivre avec leur affection en restant des personnes autonomes.
Pour cela, il y a plusieurs voies de recherche possibles. Celle que j’ai choisi est directement déduite de mes travaux précédents démontrant , dans le cerveau, l’existence de neuro-hormones (les neuro-stéroïdes), dont les effets sont en cours d’étude et les dérivés déjà démontrés très efficaces sur les animaux.
Mais ces recherches n’intéressent pas vraiment l’industrie pharmaceutique car les brevets qui en résulteront ne seront pas assez « solides » pour à ses yeux justifier des investissements. En effet les substances dérivent directement de molécules naturelles dont la formule connue n’est pas protégeable.
Pour ma part, ayant dépassé l’âge fatidique de la retraite administrative, les recherches que je conduis ne peuvent pas prétendre à des financements publics. Je fais donc appel à vous tous, qui êtes aujourd’hui en bonne santé et pourriez être de futurs malades, pour aider financièrement les recherches de mon équipe.
Les sommes nécessaires aux recherches auxquelles l’Institut veut s’atteler immédiatement, sont, pour un programme de 3 ans, de l’ordre de 4 millions d’euros. C’est relativement peu au regard des soulagements apportés et des économies réalisées en cas de succès.
J’espère susciter un mouvement d’adhésion pour financer un programme de recherche qui nous concerne tous.
Etienne E. Baulieu
Mes recherches passées et actuelles ont permis de faire une observation inédite : contrairement à ce que l’on croyait jusqu’alors, les conséquences du vieillissement du cerveau ne sont pas toutes irréversibles. Nous avons démontré qu’en administrant une hormone fabriquée dans le cerveau et déficitaire avec l’âge, on pouvait, chez le rat et la souris, leur permettre de retrouver une partie de leur faculté de mémoire, diminuée par le seul effet du vieillissement. Nous voulons savoir s’il en est de même chez l’homme, pour faire à partir de ce composé un traitement efficace, une « pilule de mémoire ».
La perte de la mémoire, donc l’abandon de la personnalité et de la dignité de l’individu, est tellement douloureuse pour la personne elle-même et insupportable, psychologiquement et économiquement, à sa famille et à son entourage…. Pour le pays entier, la charge que représente l’accompagnement médico-social, en structures d’accueil, en personnels aidant, est croissante de façon exponentielle.
L’urgence aujourd’hui, comme on ne sait pas encore guérir ni empêcher les altérations de la maladie d’Alzheimer et des autres maladies de dégénérescence cérébrale, c’est de retarder et même d’amoindrir les dégâts qu’elles provoquent. Cette stratégie scientifique peut paraître modeste : elle vise à permettre aux malades de vivre avec leur affection en restant des personnes autonomes.
Pour cela, il y a plusieurs voies de recherche possibles. Celle que j’ai choisi est directement déduite de mes travaux précédents démontrant , dans le cerveau, l’existence de neuro-hormones (les neuro-stéroïdes), dont les effets sont en cours d’étude et les dérivés déjà démontrés très efficaces sur les animaux.
Mais ces recherches n’intéressent pas vraiment l’industrie pharmaceutique car les brevets qui en résulteront ne seront pas assez « solides » pour à ses yeux justifier des investissements. En effet les substances dérivent directement de molécules naturelles dont la formule connue n’est pas protégeable.
Pour ma part, ayant dépassé l’âge fatidique de la retraite administrative, les recherches que je conduis ne peuvent pas prétendre à des financements publics. Je fais donc appel à vous tous, qui êtes aujourd’hui en bonne santé et pourriez être de futurs malades, pour aider financièrement les recherches de mon équipe.
Les sommes nécessaires aux recherches auxquelles l’Institut veut s’atteler immédiatement, sont, pour un programme de 3 ans, de l’ordre de 4 millions d’euros. C’est relativement peu au regard des soulagements apportés et des économies réalisées en cas de succès.
J’espère susciter un mouvement d’adhésion pour financer un programme de recherche qui nous concerne tous.
Etienne E. Baulieu
Bonjour Professeur,
Et bravo pour de nous permettre de suivre vos travaux et de vous soutenir grace à ce site.
Bien à vous,
Semar b.
Hi there, I dont know if I am writing in a proper board but I have got a problem with activation, link i receive in email is not working... http://www.institut-baulieu.org/?b0ed95cb868cbc78b054b67926d,
gxvhBXV
Hi there, I dont know if I am writing in a proper board but I have got a problem with activation, link i receive in email is not working... http://www.institut-baulieu.org/?5a8141faf5afcddaf2b932ef4fb,
mUFLVtg
Hi there, I dont know if I am writing in a proper board but I have got a problem with activation, link i receive in email is not working... http://www.institut-baulieu.org/?5c46d2a5d2c4f90b4e3acc0eaed,
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